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Flamma

Marcus Vinicius Candido wins ESCG award for best scientific poster at the ECVIM-CA congress

Marcus CandidoMarcus Vinicius Candido's, DVM, MSc, abstract about "Breed association of endoscopically diagnosed gastric neoplasia and metaplasia in purebred dogs" was awarded as best poster by the European Society of Comparative Gastroenterology (ESCG) at the Annual Congress of the European College of Veterinary Internal Medicine – Companion Animals (ECVIM-CA) in Gothenburg, Sweden, in September 2016.

Candido's poster presents the results of a retrospective study about the prevalence of tumors and metaplastic changes in the stomach of dogs being presented for endoscopy between 2006 and 2015.

Metaplasia consists of a local change in cellular differentiation that leads the mucosa to present characteristics resembling a different segment of the gastrointestinal tract. In humans, metaplasia and later dysplasia precede the development of adenocarcinomas. In dogs, these tumors are the most common type of gastric cancer, usually diagnosed at a very advanced stage. Early mucosal changes such as metaplasia and dysplasia tend to be difficult to detect in dogs and their role in tumor genesis in this species has yet to be defined.

- We have found a rather low overall prevalence of gastric cancer in dogs, along with a marked predisposition of Tervuren Belgian shepherds for adenocarcinoma. This is consistent with literature based on statistical reports from veterinary pathology or veterinary health insurance companies. Also metaplasia was rather rare, which is, however, likely due to the fact that these minor, flat lesions can be easily overlooked using standard white-light endoscopy, Candido mentions.

Current research focuses on more advanced imaging techniques such as chromoendoscopy and narrow band imaging to enhance visualization and directed tissue biopsy sampling of early mucosal changes which have probably been so far underdiagnosed with standard endoscopy procedures. The project is performed in cooperation between the Institute of Veterinary Science at the University of Liverpool and the Unit of Small Animal Internal Medicine at the Faculty of Veterinary Medicine in Helsinki. The supervisors of Marcus Vinicius Candido’s PhD project are the senior lecturer Peter John Noble (University of Liverpool) and professor Thomas Spillmann (University of Helsinki).

Marcus Vinicius Candido is a PhD student of the FIN-SAGAS research group at the Department of Equine and Small Animal Medicine and funded by the Brazilian Council for Science and Technology Development. He also works as endoscopy consultant and specialist in exotic animals at the University Small Animal Hospital, Helsinki.