P.O. Box 66
00014 University of Helsinki
Agnes Sj÷bergin katu 2
Faculty of Veterinary Medicine
The Faculty of Veterinary Medicine safeguards the health and wellbeing of animals and people. It is the only institution of higher education in Finland to educate veterinary surgeons. The Faculty’s operations are located at the Viikki Campus and Saari in Mäntsälä.
Public defence: Intestinal microbiota is unique to each human being and individuals can be separated by their specific faecal protein profiles
Human physiological processes are complemented by those of the microbiota, the collection of all microbes living in and on our body. The human intestinal microbiota is one of the most prominent representative and many associations with a wide spectrum of human diseases have been identified. These genes provide an enormous additional genetic potential to the human genome, but little is known about which of these genes can be expressed into proteins and the conditions under which the protein synthesis occurs. The focus of MSc Carolin Kolmeder thesis work was to increase the knowledge of the biological processes taking place in-vivo, and to establish a baseline of these functions in the intestine of a healthy adult.
Novel neurodegenerative disease and gene identified with the help of man's best friend
A breakthrough study performed in an international collaboration led by Professor Tosso Leeb from the University of Bern and Professor Hannes Lohi from the University of Helsinki together with the veterinary neurologists and neuropathologists at the Faculty of Veterinary Medicine has identified a gene mutation that causes a novel type of neurodegenerative disease in dogs. The results of the study shed light into the function of neurons, provide a new gene for human neurodegenration, and may aid in developing better treatments for neurodegenerative disorders. The study was published in the prestigious journal PLoS Genetics on 15.4.2015.
A new book on the lactating sow available
This new book published on 2015 shares up-to-date knowledge on the gestating and lactating sow. Professor Olli Peltoniemi and DVM Claudio Oliviero from the Department of Production Animal Medicine have contributed to the new book with the chapter on housing, management and environment during farrowing and early lactation.
Ingrid Hang received a post doctoral research grant from Finnish Culture Foundation
Ingrid Hang (DVM, PhD) has been awarded a one-year post doctoral research grant of 28.000 EUR from the Finnish Culture Foundation. The grant was announced on the 27 February at the Annual Gala of the Foundation.
A new inherited disease identified in calves of the Ayrshire breed
The research group led by Professor Magnus Andersson has discovered a new inherited disease that causes ptosis, retarded growth, intellectual disability and mortality in Ayrshire calves. The disease proved to be associated with a mutation in UBE3B gene. Of the 129 tested Ayrshire AI bulls recently used in Finland, 17% carried the mutation. Moreover, UBE3B mutation may be connected to AH1 haplotype, which is associated with reduced fertility and has a carrier frequency of 26.1% in the North American Ayrshire population. The study was published in BMC genomics journal on 12 October 2014.
Defence: High-protein diet plays a key role in changing the intestinal microbiota and its metabolic activity, possibly leading to intestinal inflammation and diarhhoea
Knowledge about the modulation of canine intestinal microbiota, bacteria-derived metabolic products, intestinal inflammatory status and adaptive exocrine pancreatic secretion in response to macronutrients is limited. However, such information is necessary to investigate further the complex interplay between host and intestinal microbiota in response to changes of diet. DVM Ingrid Hang's reasearch for PhD thesis focuses upon the influence of dite on intestinal microbiota, bacteria-derived metabolic products and pancreatic enzymes in dogs. Hang's research suggests that a high-protein greaves-meal diet can be associated with elevated inflammation status in dogs.
Professor Willem M. de Vos thrives with young talents
Professor Willem M. de Vos was included in the recent Thomson Reuters list of the world's most influential scientific minds of 2014. We decided to find out what is his research all about.